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Extracellular vesicle-carried GTF2I from mesenchymal stem cells promotes the expression of tumor-suppressive FAT1

Frontiers of Medicine doi: 10.1007/s11684-023-0999-5

Abstract: Through bioinformatics predictions, we identified that GTF2I and FAT1 were downregulated in thyroid carcinomaFurther, Pearson’s correlation coefficient revealed a positive correlation between GTF2I expression and FAT1The under-expression of GTF2I and FAT1 was validated in TC cell lines.Ectopically expressed GTF2I and FAT1 were found to augment malignant phenotypes of TC cells, EMT, andstemness maintenance by increasing the expression of FAT1 and facilitating the FAT1-mediated CDK4/FOXM1

Keywords： thyroid carcinoma     mesenchymal stem cell     extracellular vesicle     GTF2I     FAT1     CDK4    

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Importance of emulsions in crystallization—applications for fat crystallization

Sandra PETERSEN, K. CHALEEPA, Joachim ULRICH

Frontiers of Chemical Science and Engineering 2013, Volume 7, Issue 1,   Pages 43-48 doi: 10.1007/s11705-013-1309-6

Abstract: Here, the importance of emulsions in the field of fat crystallization is described.Three applications with industrial relevance were chosen for investigation: fat fractionation, the solidificationFor fat fractionation and phase change materials, emulsification can be applied as a tool to improvethe fat crystallization process, and thus the product quality of the crystallized fat.use of emulsification creates new application fields such as solid lipid nanoparticles in the area of fat

Keywords： emulsion     fat crystallization     phase change material     emulsion fractionation     emulsion solidification    

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Brown and beige fat: the metabolic function, induction, and therapeutic potential

Shuwen Qian,Haiyan Huang,Qiqun Tang

Frontiers of Medicine 2015, Volume 9, Issue 2,   Pages 162-172 doi: 10.1007/s11684-015-0382-2

Abstract: correlation between the brown adipose tissue activity and body mass suggests its protective role against body fat

Keywords： brown adipocyte     beige adipocyte     metabolism     obesity    

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Genome-wide association analysis reveals genetic loci and candidate genes associated with intramuscular fat

Xingwang WANG, Rongrong DING, Jianping QUAN, Linxue YANG, Ming YANG, Enqin ZHENG, Dewu LIU, Gengyuan CAI, Zhenfang WU, Jie YANG

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 3,   Pages 335-341 doi: 10.15302/J-FASE-2017152

Abstract: Intramuscular fat (IMF) is a major meat-quality trait in pigs.

Keywords： Duroc pigs     genome-wide association analysis     intramuscular fat    

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Role of exercise training on insulin resistance and TNF-α in high-fat diet rats

Hui SUN MD, Xiuling DENG MM, Fangxi XIAO MD, Lulu CHEN MD, Huiqing LI MD,

Frontiers of Medicine 2009, Volume 3, Issue 4,   Pages 403-407 doi: 10.1007/s11684-009-0071-0

Abstract: investigated the effect of exercise training on insulin resistance and serum and adipose TNF-α in high-fatrandomly divided into two groups: normal control group (NC; =8) that accepted normal chow and high-fatdiet group (HF; =22) that fed on high-fat diet to induce insulin resistance model.group (ET; =12) that performed swimming exercise training for 6 weeks, while both groups continued high-fat

Keywords： exercise training     insulin resistance     tumor necrosis factor-α    

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The Mission is Possible: Fighting Sugar and Fat for a Healthier Heart

Baofeng Yang, Rui Wang

Engineering 2023, Volume 20, Issue 1,   Pages 1-2 doi: 10.1016/j.eng.2022.10.003

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Postnatal feeding with high-fat diet induces obesity and precocious puberty in C57BL/6J mouse pups: a

Rahim Ullah, Yan Su, Yi Shen, Chunlu Li, Xiaoqin Xu, Jianwei Zhang, Ke Huang, Naveed Rauf, Yang He, Jingjing Cheng, Huaping Qin, Yu-Dong Zhou, Junfen Fu

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 266-276 doi: 10.1007/s11684-017-0530-y

Abstract:

Childhood obesity and obesity-related metabolic complications are induced by a high-fat postnatalIn the current study, we provided high-fat diet (HFD) to dams during lactation and to pups after weaningResults showed that feeding with HFD induces fat deposition and obesity in pups.

Keywords： postnatal HFD feeding     obesity     kisspeptin     HPG axis     precocious puberty    

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Multiple effects of grape seed polyphenolics to prevent metabolic diseases

Torey ARVIK, Hyunsook KIM, James SEIBER, Wallace YOKOYAMA

Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 3,   Pages 351-361 doi: 10.15302/J-FASE-2018235

Abstract: minal adipose weight gain, plasma cholesterol, liver weight gain and inflammation in animals on high fat

Keywords： grape seed     obesity     procyanidins     high fat     microbiota     animal models    

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Advancement in genetic variants conferring obesity susceptibility from genome-wide association studies

Tao Wang,Weiping Jia,Cheng Hu

Frontiers of Medicine 2015, Volume 9, Issue 2,   Pages 146-161 doi: 10.1007/s11684-014-0373-8

Abstract: numerous biological studies have been performed on the polygenic effects on obesity, such as studies on fat

Keywords： obesity     genetics     genome-wide association studies     body mass index     fat mass- and obesity-associated gene    

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Analysis of GM（1，1）Model and Its Application in Fire Risk Prediction

Chen Zijin,Wang Fuliang,Lu Shouxiang

Strategic Study of CAE 2007, Volume 9, Issue 5,   Pages 91-94

Abstract:

Theoretical analysis of grey prediction model GM(1, 1) is present inMonotonicity of predicted value and its variation tendency predicted by GM(1, 1)model is proved.the monotonicity of predicted value and its variation tendency,  applicability criterion of GM(1,1) is brought forward.

Keywords： fire forecast     GM(1     1)     rate of the fire injured    

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Metabolic interventions combined with CTLA-4 and PD-1/PD-L1 blockade for the treatment of tumors: mechanisms

Frontiers of Medicine   Pages 805-822 doi: 10.1007/s11684-023-1025-7

Abstract: To date, immune checkpoint inhibitors (ICIs) of CTLA-4 and PD-1/PD-L1 represent the main class of immunotherapyBlockade of CTLA-4 and PD-1/PD-L1 has shown remarkable efficacy in several specific types of cancers,generalized mechanism of targeting cancer metabolism at three crucial immune checkpoints (CTLA-4, PD-1,and PD-L1) to influence ICB therapy and propose potential combined immunotherapeutic strategies co-targeting

Keywords： CTLA-4     PD-1     PD-L1     immune checkpoint blockade (ICB)     metabolic reprogramming     combined tumor therapeutic    

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geological recognition breakthrough in Liaodong zone, which leading to the discovery of the large oilfield JX1-recognition breakthrough in Liaodong zone, which leading to the discovery of the large oilfield JX1-1

Deng Yunhua

Strategic Study of CAE 2011, Volume 13, Issue 10,   Pages 13-18

Abstract: According to this guidance, such giant oilfield JX1-1 was discovered with 150 million reserves in the

Keywords： Bohai Liaodong zone     JX1-1     geological recognition     large oilfield    

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Federated unsupervised representation learning Research Article

Fengda ZHANG, Kun KUANG, Long CHEN, Zhaoyang YOU, Tao SHEN, Jun XIAO, Yin ZHANG, Chao WU, Fei WU, Yueting ZHUANG, Xiaolin LI,fdzhang@zju.edu.cn,kunkuang@zju.edu.cn

Frontiers of Information Technology & Electronic Engineering 2023, Volume 24, Issue 8,   Pages 1181-1193 doi: 10.1631/FITEE.2200268

Abstract: FURL poses two new challenges: (1) data distribution shift (non-independent and identically distributed

Keywords： Federated learning     Unsupervised learning     Representation learning     Contrastive learning    

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Non-equidistant GM(1,1) power model and its application in engineering

Wang Zhengxin,Dang Yaoguo,Liu Sifeng

Strategic Study of CAE 2012, Volume 14, Issue 7,   Pages 98-102

Abstract: text-align: justify;">Aiming at the problem of modeling for non-equidistant sequence, the non-equidistant GM(1,1The results showed that the form of non equidistant GM(1,1) power model was more flexible than the traditionalBoth non equidistant GM(1,1) model and Grey Verhulst model were the special cases of non equidistantGM(1,1) power model.shows modeling accuracy in traditional modeling, which was significantly improved by non equidistant GM(1,1

Keywords： grey system     non-equidistant sequence     GM(1     1) power model     parameter optimization    

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Band-gap tunable (GaxIn1−x)2O3 layer Research Articles

Fabi Zhang, Jinyu Sun, Haiou Li, Juan Zhou, Rong Wang, Tangyou Sun, Tao Fu, Gongli Xiao, Qi Li, Xingpeng Liu, Xiuyun Zhang, Daoyou Guo, Xianghu Wang, Zujun Qin,zhangfabi@outlook.com,qinzj@guet.edu.cn

Frontiers of Information Technology & Electronic Engineering 2021, Volume 22, Issue 10,   Pages 1370-1378 doi: 10.1631/FITEE.2000330

Abstract: Multicomponent oxide (GaIn)O films are prepared on (0001) sapphire substrates to realize a tunable band-gap by technology followed by thermal annealing. The optical properties and band structure evolution over the whole range of compositions in ternary compounds (GaIn)O are investigated in detail. The X-ray diffraction spectra clearly indicate that (GaIn)O films with Ga content varying from 0.11 to 0.55 have both cubic and monoclinic structures, and that for films with Ga content higher than 0.74, only the monoclinic structure appears. The transmittance of all films is greater than 86% in the visible range with sharp absorption edges and clear fringes. In addition, a blue shift of ultraviolet absorption edges from 380 to 250 nm is noted with increasing Ga content, indicating increasing band-gap energy from 3.61 to 4.64 eV. The experimental results lay a foundation for the application of transparent conductive compound (GaIn)O thin films in photoelectric and photovoltaic industry, especially in display, light-emitting diode, and solar cell applications.

Keywords： (GaxIn1−x)2O3薄膜；带隙可调谐；磁控溅射    

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Title Author Date Type Operation

Extracellular vesicle-carried GTF2I from mesenchymal stem cells promotes the expression of tumor-suppressive FAT1

Journal Article

Importance of emulsions in crystallization—applications for fat crystallization

Sandra PETERSEN, K. CHALEEPA, Joachim ULRICH

Journal Article

Brown and beige fat: the metabolic function, induction, and therapeutic potential

Shuwen Qian,Haiyan Huang,Qiqun Tang

Journal Article

Genome-wide association analysis reveals genetic loci and candidate genes associated with intramuscular fat

Xingwang WANG, Rongrong DING, Jianping QUAN, Linxue YANG, Ming YANG, Enqin ZHENG, Dewu LIU, Gengyuan CAI, Zhenfang WU, Jie YANG

Journal Article

Role of exercise training on insulin resistance and TNF-α in high-fat diet rats

Hui SUN MD, Xiuling DENG MM, Fangxi XIAO MD, Lulu CHEN MD, Huiqing LI MD,

Journal Article

The Mission is Possible: Fighting Sugar and Fat for a Healthier Heart

Baofeng Yang, Rui Wang

Journal Article

Postnatal feeding with high-fat diet induces obesity and precocious puberty in C57BL/6J mouse pups: a

Rahim Ullah, Yan Su, Yi Shen, Chunlu Li, Xiaoqin Xu, Jianwei Zhang, Ke Huang, Naveed Rauf, Yang He, Jingjing Cheng, Huaping Qin, Yu-Dong Zhou, Junfen Fu

Journal Article

Multiple effects of grape seed polyphenolics to prevent metabolic diseases

Torey ARVIK, Hyunsook KIM, James SEIBER, Wallace YOKOYAMA

Journal Article

Advancement in genetic variants conferring obesity susceptibility from genome-wide association studies

Tao Wang,Weiping Jia,Cheng Hu

Journal Article

Analysis of GM（1，1）Model and Its Application in Fire Risk Prediction

Chen Zijin,Wang Fuliang,Lu Shouxiang

Journal Article

Metabolic interventions combined with CTLA-4 and PD-1/PD-L1 blockade for the treatment of tumors: mechanisms

Journal Article

geological recognition breakthrough in Liaodong zone, which leading to the discovery of the large oilfield JX1-recognition breakthrough in Liaodong zone, which leading to the discovery of the large oilfield JX1-1

Deng Yunhua

Journal Article

Federated unsupervised representation learning

Fengda ZHANG, Kun KUANG, Long CHEN, Zhaoyang YOU, Tao SHEN, Jun XIAO, Yin ZHANG, Chao WU, Fei WU, Yueting ZHUANG, Xiaolin LI,fdzhang@zju.edu.cn,kunkuang@zju.edu.cn

Journal Article

Non-equidistant GM(1,1) power model and its application in engineering

Wang Zhengxin,Dang Yaoguo,Liu Sifeng

Journal Article

Band-gap tunable (GaxIn1−x)2O3 layer

Fabi Zhang, Jinyu Sun, Haiou Li, Juan Zhou, Rong Wang, Tangyou Sun, Tao Fu, Gongli Xiao, Qi Li, Xingpeng Liu, Xiuyun Zhang, Daoyou Guo, Xianghu Wang, Zujun Qin,zhangfabi@outlook.com,qinzj@guet.edu.cn

Journal Article